This study was designed to isolate the strains of the tonsillar surface and core and study the beta-lactamase activity of them. 103 pediatric patients who were performed tonsillectomy and adenoidectomy from September 1990 to February 1991 at Department of Otolaryngology of Chung Ang University Hospital were divided into the recurrent tonsillitis group and the simple enlarged_ tonsil group in this study.
The results were as follows;
1) The numbers of patients in recurrent tonsillitis group were 63 cases and those in simple en Wge-d tonsil group were 40 cases.
2) In the recurrent tonsillitis group, alpha-hemolytic streptococcus (60 cases), Neisseria species (56 cases) and Staphylococcus aureus (7 cases) were cultured from the surface of tonsil. Alpha-hemolytic -~reptacoccus (58 cases), Neiserria species (48 cases) and Staphylococcus aureus (9 cases) were cultured lir M the core of tonsil.
3) In simple enlarged tonsil group, alpha-hemolytic streptococcus (39 cases), Neisseria species (37 9ks) and Staphylococcus aureus (4 cases) were cultured from the surface of tonsil. Alpha-hemolytic 46ptococcs´(35 cases), Neisseria species (30 cases) and Staphylococcus aureus 11 cases) were cultured
m the core of tonsil.
4) The numbers of patients from which beta-lactamase-producing bacteria were detected were L "cases (26.21%) and these organisms were sensitive to oxacillin, clindamycin, chloramphenicol, r -tnicin, and. cephalosporin.
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